AZITHROMYCIN MONOHYDRATE Ritemed 500 milligrams
Generic Name: AZITHROMYCIN MONOHYDRATE
Brand Name: Ritemed
Dosage Strength: 500 milligrams
Dosage Form: Film-coated Tablet
WHAT IS THE MEDICINE USED FOR?
- Lower respiratory tract infections, including bronchitis and mild to moderately severe community acquired pneumonia.
- Upper respiratory tract infections, including sinusitis and pharyngitis/ tonsillitis (azithromycin monohydrate is not the substance of first choice for the treatment of pharyngitis and tonsillitis caused by Streptococcus pyogenes. For this and for the prophylaxis of acute rheumatic fever penicillin is the treatment of first choice)
- Inflammations of the middle ear
- Skin and soft tissue infections
- Uncomplicated Chlamydia trachomatis urethritis and cervicitis
HOW MUCH AND HOW OFTEN SHOULD YOU USE THIS MEDICINE?
Children and adolescents over 45 kg body weight and adults, including the elderly
- The total dosage of azithromycin monohydrate is 1500 mg which is spread either over three days (500 mg once daily) or over five days (500 mg as a single dose on the first day and thereafter 250 mg once daily).
In uncomplicated Chlamydia trachomatis urethritis and cervicitis the dosage is 1000 mg per os as a single dose.
Method of Administration
- Azithromycin monohydrate 500 mg should be administered as a single daily dose.
- Azithromycin monohydrate 500 mg can be taken independently of the meals.
- When taking antacids such as aluminum hydroxide, magnesium carbonate
- When taking digoxin
(Precautions) Allergic reactions including angioedema & anaphylaxis. Significant hepatic disease. Monitor liver function tests. Co-administration w/ ergot derivatives. Consider Clostridium difficile associated diarrhea (CDAD) in patients who present w/ diarrhea after use. Severe renal impairment (CFR <10 mL/min); congenital or documented QT prolongation, currently receiving treatment w/ other active substances known to prolong QT interval eg class IA & III antiarrhythmics, cisapride & terfenadine, electrolyte disturbance particularly in cases of hypokalemia & hypomagnesemia, clinically relevant bradycardia, cardiac arrhythmia or severe cardiac insufficiency. Exacerbations of myasthenia gravis symptoms. Not for prevention or treatment of Mycobacterium avium complex in childn. Rare hereditary problems of galactose intolerance, Lapp lactase deficiency or glucose-galactose malabsorption. Pregnancy & lactation. Childn & adolescents <45 kg body wt.
(Adverse Reactions) Diarrhea, abdominal pain, nausea, flatulence. Anorexia, dizziness, headache, paresthesia, dysgeusia, visual impairment, deafness, vomiting, dyspepsia, rash, pruritus, arthralgia, fatigue, decreased lymphocyte count, increased eosinophil count, decreased blood bicarbonate.
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