Simvastatin 40mg

SIMVASTATIN Ritemed 40 milligrams

SIMVASTATIN

Ritemed

Generic Name: SIMVASTATIN
Brand Name: Ritemed
Dosage Strength: 20 milligrams
Dosage Form: Tablet

WHAT IS THE MEDICINE USED FOR?
(Indication) It is used in patients with hyperlipidemia, coronary heart disease and hypercholesterolemia to decrease the risk of fatal and non-fatal myocardial infarction and decrease the incidence of stroke and transient ischemic attacks.
 HOW MUCH AND HOW OFTEN SHOULD YOU USE THIS MEDICINE? 

Coronary Heart Disease

  • Initial Dose: 20 mg once daily at bedtime
  • May be increased at intervals of not less than 4 weeks to a maximum of 80 mg
  • once daily given as a single dose at bedtime.

Hyperlipidemia

  • Initial Dose: 20 mg once daily at bedtime
  • Patients who require only a moderate reduction of LDL-C may be started at 10 mg once daily at bedtime.

Homozygous Familial Hypercholesterolemia

  • Initial Dose: 40 mg once daily at bedtime or 80 mg/day in 3 divided doses of 20 mg, 20mg and 40 mg given in the morning, afternoon and evening, respectively.

Renal Insufficiency

  • Initial Dose: 5 mg once daily at bedtime with close monitoring
  • Initiating therapy in patients with severe renal insufficiency (creatinine clearance <30 mL/min) at a dose above 10 mg/day should be considered carefully and implemented cautiously.
  • Dose modification should not be necessary in patients with mild to moderate renal impairment because simvastatin does not undergo substantial renal excretion.

Or, as prescribed by a physician.

(Contraindications)

  • Erythromycin, Clarithromycin: increased risk of muscle pain and weakness
  • Niacin: increased risk of muscle pain and weakness
  • Grapefruit juice: increased risk of muscle pain and weakness
  • Itraconazole, Ketoconazole: increased risk of muscle pain and weakness
  • Nelfinavir, Ritonavir, Saquinavir: increased risk of liver damage
  • Diagnosed with liver disease, rhabdomyolysis

(Precautions) Monitor liver enzyme levels periodically. Alcoholics & patients w/ liver disease.

(Adverse Reactions) Constipation, dyspepsia, flatulence, pain, diarrhea, asthenia, nausea/vomiting & headache. Rhabdomyolysis w/ acute renal failure secondary to myoglobinuria occurred rarely & requires discontinuance.

SRP: 20.00

Category:

Disclaimer: The contents of this site are for information purposes only and should not be construed as a susbtitute for professional medical advice. For diagnosis, treatment and prescription, consult your physician and other healthcare providers. Carefully read all product labels and packaging prior to use.

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