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  • Rx: TGP Gliclazide 60mg MRTablet
  • Rx: TGP Gliclazide 60mg MRTablet
  • Rx: TGP Gliclazide 60mg MRTablet
  • Rx: TGP Gliclazide 60mg MRTablet

Rx: TGP Gliclazide 60mg MRTablet

Prescription Medicines (TGP) TGP
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Gliclazide is an oral medication used for the management of type 2 diabetes mellitus. It is classified as a sulfonylurea, which helps lower blood glucose levels by stimulating the pancreas to release more insulin. The "MR" stands for "Modified Release," indicating that the tablet is designed to release gliclazide gradually over time.

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Description:

1. Formulation
o Strength: Each modified-release (MR) tablet contains 60 mg of gliclazide.
o Formulation: Modified-release tablets are formulated to provide a slow and sustained release of gliclazide, allowing for once-daily dosing and more stable blood glucose control over the course of the day.

2. Indications
Gliclazide 60 mg MR is prescribed to manage blood glucose levels in patients with type 2 diabetes mellitus. It is used in conjunction with diet and exercise when these alone are insufficient to control blood glucose levels. The modified-release formulation helps in maintaining a more consistent glucose level throughout the day.

3. Age Groups
o Adults: Gliclazide 60 mg MR is generally used in adults. The usual starting dose is one 60 mg MR tablet daily, with adjustments based on individual blood glucose monitoring and response.
o Elderly: Dosage adjustments may be required for elderly patients due to potential changes in renal or hepatic function, which could affect drug metabolism.
o Children: Gliclazide is not recommended for use in children or adolescents.

4. Contraindications
Gliclazide should not be used in the following conditions:

o Type 1 Diabetes Mellitus: Gliclazide is not effective for type 1 diabetes, where insulin production is absent.
o Diabetic Ketoacidosis: It is contraindicated in patients with diabetic ketoacidosis, which requires insulin therapy.
o Severe Renal Impairment: Use is contraindicated in patients with severe renal impairment due to the risk of drug accumulation and hypoglycemia.
o Severe Hepatic Impairment: It should be avoided in individuals with severe liver dysfunction, as it can affect drug metabolism.
o Hypersensitivity to Sulfonylureas: Known allergy or hypersensitivity to gliclazide or other sulfonylureas is a contraindication.
o Pregnancy and Breastfeeding: Gliclazide is not recommended during pregnancy or breastfeeding. Alternative treatments should be used in these situations.

5. Additional Considerations
o Risk of Hypoglycemia: Gliclazide can cause low blood sugar (hypoglycemia), especially if meals are missed or if used in combination with other glucose-lowering medications. Monitoring of blood glucose levels is essential.
o Drug Interactions: Gliclazide can interact with various medications, including corticosteroids, diuretics, and other antidiabetic drugs. Inform your healthcare provider of all medications you are taking.

Always use gliclazide under the guidance of a healthcare provider, who will tailor the dosage and monitor for side effects based on individual needs and responses.

TGP
4806526157206
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Data sheet

Category Level 1:
Prescription Medicines (TGP)
Category Level 2:
Antidiabetic & Insulins

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