Rx: TGP Losartan Potassium+Amlodipine 50mg/5mg FCTablet

1. Formulation
o Form: Film-coated tablet
o Dosage: Each tablet contains 50 mg of Losartan Potassium and 5 mg of Amlodipine.

2. Indications
oPrimary Use: Treatment of essential hypertension (high blood pressure).
o Secondary Uses: It may also be used for patients with chronic kidney disease or diabetes-related kidney problems, often as part of a broader therapeutic strategy.

3. Age Groups
o Adults: This medication is typically prescribed to adult patients.
o Children and Adolescents: The safety and efficacy in children and adolescents have not been well-established, so this combination is generally not recommended for these age groups unless specifically directed by a healthcare provider.

4. Contraindications
o Hypersensitivity: Contraindicated in patients with known hypersensitivity to Losartan, Amlodipine, or any of the tablet's components.
o Pregnancy: Not recommended during pregnancy, especially in the second and third trimesters, due to potential risks to the fetus.
o Severe Liver Impairment: Caution is advised in patients with severe liver impairment; Losartan is metabolized in the liver, and Amlodipine can affect liver function.
o Severe Renal Impairment: Use with caution in patients with severe renal impairment, as both drugs can affect kidney function.
o Aortic Stenosis: Caution is needed in patients with significant aortic stenosis due to potential for increased adverse effects.

Always consult with a healthcare professional for a comprehensive assessment tailored to individual health needs and conditions.