Mp Felodipine Tab 10mg (lodine Sandoz) 20

MP-Felodipine Tab 10mg (LODINE SANDOZ)-20

MP-Felodipine Tab 10mg (LODINE SANDOZ)-20
Indications:
Treatment for Essential hypertension/Stable angina pectoris.
Dosage and Administration:
The tablets should be taken in the morning and be swallowed with water. In order to keep the prolonged release properties, the tablets must not be divided, crushed or chewed. The tablets can be administered without food or following a light meal not rich in fat or carbohydrate.

Hypertension: The dose should be adjusted individually. Treatment can be started with 5mg once daily. Depending on the patient’s response, the dosage can, where applicable, be decreased to 2.5mg or increased to 10mg. The standard maintenance dose is 5mg once daily.

Stable angina pectoris: The dose should be adjusted individually. Treatment should be initiated with 5mg once daily and, if needed, increased to 10mg once daily. Elderly population: Initial treatment with lowest available dose should be considered.

Renal impairment: Dose adjustment is not needed in patients with impaired renal function. Hepatic impairment: Patients with impaired hepatic function may have elevated plasma concentrations of felodipine and may response to lower doses.

Pediatric population: There is limited clinical trial experience of the use of felodipine in hypertenseive pediatric patients.
Contraindications:
Pregnancy – Known hypersensitivity to felodipine or to any of the excipients – Uncompensated heart failure – Acute myocardial infraction – Unstable angina pectoris – Hademodynamically significant cardiac valvular obstruction – Dynamic cardiac outflow obstruction – Cardiogenic shock
Precautions:
Felodipine may cause significant hypotension with subsequent tachycardia. This may lead to myocardial ischaemia in suspectible patients. Felodipine must be used with caution in patients with a propensity for tachycardia. Felodipine is cleared by the liver. Consequently can higher therapeutic concentrations and response be expected in patients with clearly reduced liver function. Excipients with known effect: The tablets contain lactose. Patients with rare hereditary problems of galactose intolerance, the Lapp lactase deficiency or glcuose-galactose malabsorption should not take this medicine.
Side Effects:
Headache, Dizziness, Paraesthesia, Tachycardia, Paliptations, Flush, Syncope, Nausea, Abdominal pain, Vomiting, Gingival hyperplasia, gingivitis, Increased liver enzymes, Rash, pruritus, Urticaria, Photosensitivity reactions, Leucocytolastic vasculitis, Arthalgia, Myalgia, Pollakisuria, Impotence / Sexual dysfunction, Peripheral oedema, Fatigue, Angio-oedema, Fever.


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