DEXAMETHASONE SODIUM PHOSPHATE Dabrin 4 milligrams/milliliters 2 milliliters
DEXAMETHASONE SODIUM PHOSPHATE
Generic Name: DEXAMETHASONE SODIUM PHOSPHATE
Brand Name: Dabrin
Dosage Strength: 4 milligrams/milliliters 2 milliliters
Dosage Form: Solution for Injection
WHAT IS THE MEDICINE USED FOR?
(Indication) Asthma & related bronchospastic disorder unresponsive to other therapy, allergic rhinitis, inflammatory nasal condition. Also used in cerebral edema due to malignancy.
HOW MUCH AND HOW OFTEN SHOULD YOU USE THIS MEDICINE?
(Dosage) Severe shock IV 2-6 mg/kg body wt. Cerebral edema due to malignancy IV 10 mg followed by 4 mg IM 6 hrly. IA inj 0.8-4 mg. Soft-tissue inj 2-6 mg.
(Contraindications) Neonate & infant.
(Precautions) Caution use in heart failure, recent MI, HTN, DM, epilepsy, glaucoma, hypothyroidism, hepatic failure, osteoporosis, peptic ulcer, psychoses, severe affective disorders, renal impairment. Reduce Ca & K intake. Monitor fluid intake & output, & wt daily. Rapid IV inj of massive dose may cause CV collapse. Childn. Elderly.
(Adverse Reactions) Risk of osteoporosis & spontaneous fracture, muscle wasting, nitrogen depletion, hyperglycemia. Increased insulin requirement in diabetics, increased appetite. Menstrual irregularities, amenorrhea, hyperhidrosis, skin thinning, ocular changes including development of glaucoma & cataract, neurological disturbances, benign intracranial HTN, acute pancreatitis, avascular necrosis of the bone. Increased blood coagulation that may lead to thromboembolic complication. Peptic ulcer. Adrenal atrophy, secondary adrenocortical insufficiency. Paresthesia & irritation, epidural lipomatosis.
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