Etoricoxib T60mg Arcoxia

ETORICOXIB Arcoxia™Ac 60 milligrams

ETORICOXIB

Arcoxia™Ac

Generic Name: ETORICOXIB
Brand Name: Arcoxia™Ac
Dosage Strength: 60 milligrams
Dosage Form: Tablet

WHAT IS THE MEDICINE USED FOR?

(Indication) Acute and chronic treatment of the signs and symptoms of osteoarthritis (OA) and rheumatoid arthritis (RA); treatment of ankylosing spondylitis (AS); treatment of acute gouty arthritis; relief of acute pain; treatment of primary dysmenorrhea; treatment of moderate to severe acute post-operative pain associated with dental surgery; treatment of moderate to severe acute post-operative pain associated with abdominal gynecological surgery.

The decision to prescribe a selective COX-2 inhibitor should be based on an assessment of the individual patient's overall risks

HOW MUCH AND HOW OFTEN SHOULD YOU USE THIS MEDICINE?

(Dosage)

Arthritis, Osteoarthritis: The recommended dose is 30 mg or 60 mg once daily.

Doses greater than those recommended for each indication have either not demonstrated additional efficacy or have not been studied. Therefore: The dose for OA should not exceed 60 mg daily.

As the cardiovascular risks of selective COX-2 inhibitors may increase with dose and duration of exposure, the shortest duration possible and the lowest effective daily dose should be used. The patient's need for symptomatic relief and response to therapy should be re-evaluated periodically

Elderly, Gender, Race: No dosage adjustment in ETORICOXIB (ARCOXIA) is necessary for the elderly or based on gender or race.
Hepatic Insufficiency: In patients with mild hepatic insufficiency (Child-Pugh score 5-6), a dose of 60 mg once daily should not be exceeded. In patients with moderate hepatic insufficiency (Child-Pugh score 7-9), the dose should be reduced; a dose of 60 mg every other day should not be exceeded, administration of 30 mg once daily can also be considered. There are no clinical or pharmacokinetic data in patients with severe hepatic insufficiency (Child-Pugh score >9)

(Contraindications) Hypersensitivity to etoricoxib or to any of the excipients. Active peptic ulceration or active gastro-intestinal (GI) bleeding; patients who have experienced bronchospasm, acute rhinitis, nasal polyps, angioneurotic oedema, urticaria, or allergic-type reactions after taking acetylsalicylic acid or NSAIDS including COX-2 (cyclooxygenase-2) inhibitors; severe hepatic dysfunction (serum albumin <25g/l or Child-Pugh score≥10); estimated renal creatinine clearance <30 mL/min; children and adolescents under 16 years of age; inflammatory bowel disease; congestive heart failure (NYHA II-IV); patients with hypertension whose blood pressure has not been adequately controlled; established ischemic heart disease, peripheral arterial disease and/or cerebrovascular disease.

(Precautions) Use at the shortest possible duration & the lowest effective daily dose to avoid CV risk. Not a substitute for aspirin for CV prophylaxis. Patients at risk of CV events (HTN, Hyperlipidemia, DM, smoking), w/ peripheral arterial disease, or w/ preexisting edema, impaired renal function, HTN or uncompensated heart failure or cirrhosi; considerable dehydratio. History of GI perforation, ulcers & bleeding. Elderly over 65 yrs.

(Adverse Reactions) Asthenia/fatigue, dizziness, lower extremity edema, HTN, dyspepsia, heartburn, nausea, increased ALT & AST, Thrombocytopenia, hypersensitivty reactions including anaphylactic/anaphylactoid reactions including shock; hyperkalemia, anxiety, insomia, confusion, hallucinations, depression, restlessness; dysgeusia, somnolence, blurred vision, CHF, palpitations, angina, arrythmia, hypertensive crisis, bronchospasm, abdominal pain, oral ulcers, peptic ulcer including perforation or bleeding (elderly), vomiting, diarrhea, hepatitis, jaundice; hepatic failure, angioedema, pruritus, erythema, rash, Stevens-Johnson syndrome, toxic epidermal necrolysis, urticaria; fixed-drug eruption, renal insufficiency including renal failure.


Disclaimer: The contents of this site are for information purposes only and should not be construed as a susbtitute for professional medical advice. For diagnosis, treatment and prescription, consult your physician and other healthcare providers. Carefully read all product labels and packaging prior to use.

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