FEBUXOSTAT 40 mg Tablet (Atenurix)
Generic Name: FEBUXOSTAT
Brand Name: Atenurix
Dosage Strength: 40 milligrams
Dosage Form: Tablet
WHAT IS THE MEDICINE USED FOR?
(Indication) Treatment of chronic hyperuricemia in conditions where urate deposition has already occurred (including a history or presence of tophus &/or gouty arthritis).
HOW MUCH AND HOW OFTEN SHOULD YOU USE THIS MEDICINE?
Adult 20-40 mg once daily. May be increased to 120 mg once daily if serum uric acid is >6 mg/dL after 2-4 wk. Hepatic impairment 80 mg/day.
(Contraindications) Hypersensitivity. Pregnancy & lactation.
(Precautions) Do not use until acute gouty attacks (gout flare) has completely subsided. Not recommended for patients w/ ischemic heart disease or CHF; xanthine deposition (eg malignant disease or Lesch-Nyhan syndrome); altered thyroid function. Perform liver function test prior to treatment & periodically thereafter. Severe renal & hepatic impairment. Childn <18 yr.
(Adverse Reactions) Liver function abnormalities, diarrhea, headache, nausea & rash.
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