The tablets should be taken in the morning and be swallowed with water. In order to keep the prolonged release properties, the tablets must not be divided, crushed or chewed. The tablets can be administered without food or following a light meal not rich in fat or carbohydrate. Hypertension: The dose should be adjusted individually. Treatment can be started with 5mg once daily. Depending on the patient’s response, the dosage can, where applicable, be decreased to 2.5mg or increased to 10mg. The standard maintenance dose is 5mg once daily.
Stable angina pectoris: The dose should be adjusted individually. Treatment should be initiated with 5mg once daily and, if needed, increased to 10mg once daily. Elderly population: Initial treatment with lowest available dose should be considered.
Renal impairment: Dose adjustment is not needed in patients with impaired renal function.
Hepatic impairment: Patients with impaired hepatic function may have elevated plasma concentrations of felodipine and may response to lower doses.
Pediatric population: There is limited clinical trial experience of the use of felodipine in hypertenseive pediatric patients.