Irbesartan Tab 300mg (IRBEGEN)-30
It is used in the management of hypertension and treatment of renal disease in hypertensive type II diabetes mellitus patients.
Dosage and Administration:
Hypertension: initially 150mg once daily, increased if necessary to 300mg once daily or as presribed by the physician.
Renal disease in hypertensive type II diabetes mellitus: initially 150mg once daily or as prescribed by the physician.
Irbesartan is contraindicated in pregnancy and should be used with care, if at all, during breastfeeding. It should be used with caution in patients with renal artery stenosis. Reduced doses may be required in patients with renal impairment and should be considered in patients with hepatic impairment. Patients with volume depletion (for example those who have received high-dose diuretic therapy) may experience hypotension, which may be minimized by initiating treatment with a low dose of Irbesartan. Since hyperkalaemia may occur, serum-potassium concentrations should be monitored expecially in the elderly and patients with renal impairment, and the concomitant use of potassium-sparing diuretics should be generally be avoided.
Adverse effects of Irbesartan have been reported to be usually mild and transient, and include dizziness and dose-related orthostatic hypotension. Hypotension may occur particularly in patients with volume depletion (for example those who have received high-dose diuretics.). Impaired renal function and rarely, rash, angioedema, and raised liver enzyme values may occur. Hyperkalaemia, myalgia and arthralgia have been reported. Irbesartan appears less likely than ACE inihibitors to cause cough. Other adverse effects that have been rpoerted iwth angiotensin II receptor antagonists include respirator-tract disorders, back pain, gastrointestinal disturbances, fatigue, and neutropenia.
Disclaimer: The contents of this site are for information purposes only and should not be construed as a susbtitute for professional medical advice. For diagnosis, treatment and prescription, consult your physician and other healthcare providers. Carefully read all product labels and packaging prior to use.