METHAZOL Methimazole Tablet 20 mg
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DESCRIPTION
METHAZOL Methimazole Tablet 20 mg contains methimazole, an antithyroid medication used to reduce the production of thyroid hormones. It works by inhibiting iodine incorporation into thyroid hormone synthesis, thereby lowering levels of thyroxine (T4) and triiodothyronine (T3). This helps restore normal thyroid function in patients with hyperthyroidism.
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USES
• Treatment of hyperthyroidism
• Management of Graves’ disease
• Preparation of patients with hyperthyroidism prior to thyroid surgery
• Control of hyperthyroidism before and after radioactive iodine therapy
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DOSAGE
• Dosage is individualized based on disease severity and patient response
• Adults: Initial and maintenance doses are determined by a healthcare professional
• Usually taken once to three times daily, with or without food
• Regular monitoring of thyroid function tests (TSH, T3, T4) is necessary
• Do not stop or change dose without medical advice
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PRECAUTIONS
• Use with caution in patients with liver impairment
• Monitor for signs of agranulocytosis (e.g., fever, sore throat, infection); discontinue and seek medical attention immediately if these occur
• Periodic complete blood counts (CBC) and liver function tests are recommended
• Use with caution during pregnancy; lowest effective dose should be used if prescribed
• Methimazole may pass into breast milk; consult a healthcare professional before breastfeeding
• Inform the physician of all medications being taken
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SIDE EFFECTS
Common side effects may include:
• Nausea or stomach upset
• Skin rash or itching
• Headache
Serious but rare side effects:
• Agranulocytosis
• Hepatotoxicity
• Joint pain
• Vasculitis
Seek immediate medical attention if signs of infection, jaundice, or severe reactions occur.
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STORAGE
• Store at room temperature, below 30 °C
• Keep in a dry place, protected from moisture and heat
• Keep out of reach of children