TGP Glimepiride plus Metformin Tablet 2 mg / 500 mg
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DESCRIPTION
TGP Glimepiride plus Metformin Tablet 2 mg / 500 mg is a fixed dose combination oral antidiabetic medication used in the management of Type 2 Diabetes Mellitus. Glimepiride is a sulfonylurea that stimulates insulin secretion from pancreatic beta cells, while metformin is a biguanide that reduces hepatic glucose production and improves insulin sensitivity. The combination provides complementary mechanisms to improve glycemic control.
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USES
• Management of Type 2 Diabetes Mellitus
• Improves blood glucose control in patients inadequately controlled on monotherapy
• Used as an adjunct to diet, exercise, and lifestyle modification
• Helps control both fasting and post prandial blood glucose levels
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DOSAGE
• Dosage should be determined by a healthcare professional
• Common adult dose: one tablet once or twice daily, taken with meals
• Dose adjustments should be based on blood glucose response
• Tablets should be swallowed whole with water
• Do not skip meals while taking this medication
• Regular monitoring of blood glucose is recommended
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PRECAUTIONS
• Prescription only medicine; use under medical supervision
• Not indicated for Type 1 Diabetes Mellitus or diabetic ketoacidosis
• Use with caution in elderly patients and those with renal or hepatic impairment
• Risk of hypoglycemia, especially with missed meals, excessive exercise, or alcohol intake
• Metformin associated risk of lactic acidosis, particularly in renal dysfunction
• Temporary discontinuation may be required before radiologic procedures using iodinated contrast
• Inform the healthcare provider of all concurrent medications
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SIDE EFFECTS
• Hypoglycemia (sweating, tremors, dizziness, hunger)
• Nausea or vomiting
• Diarrhea or abdominal discomfort
• Headache
• Weight gain
• Rarely, lactic acidosis or liver function abnormalities
Seek immediate medical attention if symptoms of severe hypoglycemia, muscle pain, extreme fatigue, or breathing difficulty occur.
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STORAGE
• Store at room temperature, below 30°C
• Protect from moisture and heat
• Keep the container tightly closed
• Keep out of reach of children