ABDIN Aripiprazole Tablet 10 mg
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DESCRIPTION
ABDIN Aripiprazole Tablet 10 mg contains aripiprazole, an atypical antipsychotic with a unique mechanism of action. It functions as a partial agonist at dopamine D₂ and serotonin 5 HT₁A receptors and an antagonist at serotonin 5 HT₂A receptors, helping to stabilize dopamine and serotonin activity in the brain. This balanced activity contributes to improvement in mood, behavior, and cognition with a comparatively lower risk of certain adverse effects.
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USES
• Treatment of schizophrenia
• Management of bipolar disorder, including:
o Acute manic and mixed episodes
o Maintenance therapy
• Adjunct therapy for major depressive disorder (as prescribed)
• Management of irritability associated with autistic disorder
• Other psychotic or mood disorders, as directed by a physician
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DOSAGE
• Dosage is individualized based on indication, patient response, and tolerability
• Adults: A typical therapeutic dose may include 10 mg once daily, adjusted as needed by a healthcare professional
• May be taken once daily, with or without food
• Tablets should be taken at the same time each day
• Do not discontinue abruptly without medical advice
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PRECAUTIONS
• Use with caution in patients with cardiovascular disease, diabetes mellitus, seizure disorders, or hepatic impairment
• Monitor for metabolic changes (weight gain, blood glucose, lipid levels)
• Increased risk of suicidal thoughts in children, adolescents, and young adults during early treatment—close monitoring is recommended
• May cause orthostatic hypotension, especially during initiation or dose adjustments
• Not recommended in elderly patients with dementia related psychosis
• Use during pregnancy or breastfeeding only if clearly needed and prescribed
• Inform the healthcare provider of all concomitant medications
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SIDE EFFECTS
Common side effects may include:
• Akathisia (restlessness)
• Headache
• Insomnia or sleep disturbances
• Anxiety
• Nausea or vomiting
Less common or serious side effects:
• Weight gain
• Metabolic changes (elevated blood sugar or lipids)
• Extrapyramidal symptoms
• Neuroleptic malignant syndrome (rare but serious)
• Allergic reactions
Seek immediate medical attention if severe restlessness, muscle rigidity, high fever, or unusual behavior changes occur.
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STORAGE
• Store at room temperature, below 30 °C
• Keep in a dry place, protected from moisture and heat
• Keep out of reach of children