IRBEGEN Irbesartan 300mg Tablet

How much and how often should you use the product? Irbesartan tablets are taken orally. Consult your doctor on the right dosage or number of tablets you should be taking each day based on your age, overall health, and medical conditions. Do not take it in larger amounts or for longer than recommended. Usual Adult Dose for Hypertension: Initial dose: 150 mg orally once a day Maximum dose: 300 mg orally once a day Usual Adult Dose for Diabetic Nephropathy: Target maintenance dose: 300 mg orally once a day Mechanism of Action Irbesartan works by preventing angiotensin II from binding to the AT receptor in tissues such as the vascular smooth muscle and the adrenal gland. Irbesartan and its active metabolite then bind the AT1 receptor with 8,500 times more affinity than they bind to the AT2 receptor. Because Irbesartan prevents angiotensin II from binding to AT receptors, it allows the vascular smooth muscles to relax and prevents the secretion of aldosterone, then effectively lowering the patient?s blood pressure. Without irbesartan, angiotensin II would be able to bind to the AT1 receptor bringing about vasoconstriction and aldosterone secretion, leading to raised blood pressure. Before using this medication notify your doctor if you have or are: Kidney disease Liver disease Congestive heart failure Pregnant, are planning to become pregnant, or are nursing a baby Below are the possible side effects that you may experience from taking irbesartan tablets. These side effects are possible but do not always occur. If you experience any of these side effects, stop taking the product and immediately consult with your doctor. A light-headed feeling, like you might faint Little or no urination Swelling, rapid weight gain Confusion, loss of appetite, vomiting, pain in your side or lower back High potassium level?nausea, weakness, tingly feeling, chest pain, irregular heartbeats, loss of movement Irbesartan tablets are available in all The Generics Pharmacy branches nationwide at a very affordable price.